Easy Low Carb Chicken Casserole is a simple, comforting dish that combines tender chicken, creamy cheese, and fresh veggies—all baked together into a warm, satisfying meal. It’s perfect if you’re looking for something tasty but want to keep the carbs in check. The golden, cheesy top and the juicy chicken underneath make every bite a treat without feeling heavy.
I love making this casserole on busy weeknights because it comes together quickly and uses ingredients I usually have on hand. Plus, it’s a great way to sneak in some vegetables without anyone noticing! I usually add a little extra cheese on top for that perfect gooey finish, and it never disappoints.
When I serve this casserole, I like to pair it with a crisp green salad or some steamed broccoli to keep the meal light and fresh. It’s one of those dishes that feels like a warm hug on the plate, and it always brings smiles around the dinner table. If you want a fuss-free, delicious chicken dinner that’s low in carbs but big on flavor, this casserole is a go-to in my house.
Key Ingredients & Substitutions
Chicken breasts: I recommend using boneless, skinless chicken breasts for lean protein. You can use thighs if you want a juicier texture or leftover cooked chicken to save time.
Sour cream & mayonnaise: These add creaminess and flavor. If you want fewer calories, try Greek yogurt instead of sour cream. For a dairy-free version, use avocado mayo.
Cheese: Cheddar, mozzarella, and Parmesan create a cheesy, melty topping. For a sharper flavor, add more Parmesan or swap mozzarella with provolone or gouda.
Garlic & herbs: Minced garlic and dried parsley or Italian seasoning bring nice flavor without carbs. Fresh herbs like basil or thyme can also be used if you prefer.
Veggies (optional): Spinach or steamed broccoli are great low-carb options to add nutrition and color. You could also try zucchini or cauliflower for variety.
How Do You Ensure the Chicken Stays Tender and Juicy?
Cooking chicken in a creamy sauce helps keep it tender and moist. Here’s what I recommend:
- Season the chicken well with salt and pepper before baking for good flavor inside.
- Spread some creamy sauce on the bottom of the dish first to stop the chicken from sticking and dry cooking.
- Cover the chicken fully with the sauce before baking to lock in moisture.
- Bake uncovered for a golden top but watch the cooking time carefully—about 35-40 minutes, or until the internal temperature hits 165°F (74°C).
- Let the casserole rest a few minutes after baking to let juices redistribute, making it more tender when you cut into it.
Equipment You’ll Need
- 9×13-inch baking dish – perfect size for even cooking and easy serving.
- Mixing bowl – use this to combine your creamy sauce ingredients smoothly.
- Measuring cups and spoons – helps get the right cheese and seasoning amounts.
- Sharp knife and cutting board – for prepping chicken and optional veggies.
- Oven mitts – to safely handle the hot casserole dish when taking it out of the oven.
Flavor Variations & Add-Ins
- Swap chicken breasts for cooked shredded rotisserie chicken to save time and add extra flavor.
- Add cooked bacon bits for a smoky crunch that complements the creamy cheese sauce.
- Stir in chopped mushrooms or roasted bell peppers for added texture and taste.
- Use pepper jack cheese instead of cheddar for a little spicy kick.
Easy Low Carb Chicken Casserole
Ingredients You’ll Need:
Main Ingredients:
- 4 boneless, skinless chicken breasts
- 1 cup sour cream
- 1 cup mayonnaise
- 1 cup shredded cheddar cheese
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- 2 cloves garlic, minced
- 1 tbsp dried parsley or Italian seasoning
- Salt and pepper to taste
- Optional: 1 cup chopped fresh spinach or steamed broccoli for added veggies
How Much Time Will You Need?
This casserole takes about 10 minutes to prepare and about 35 to 40 minutes to bake. Add an extra 5 minutes to let it rest before serving. So, plan for around 50 minutes total from start to finish.
Step-by-Step Instructions:
1. Prepping the Oven and Dish:
Start by preheating your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish so your casserole won’t stick.
2. Preparing the Chicken:
Season your chicken breasts with salt and pepper on both sides. You can leave them whole or cut into bite-sized pieces if you like smaller portions.
3. Mixing the Creamy Sauce:
In a medium bowl, mix the sour cream, mayonnaise, minced garlic, half of the cheddar cheese, half of the mozzarella, Parmesan cheese, and dried parsley or Italian seasoning. Stir everything together until smooth and well combined. If you’re adding spinach or broccoli, fold it in now.
4. Assembling the Casserole:
Spread a thin layer of the creamy mixture on the bottom of your baking dish. Arrange the chicken breasts evenly over the sauce or scatter the pieces if cut. Then spoon the remaining creamy mixture to cover the chicken well.
5. Adding Cheese and Baking:
Sprinkle the rest of the cheddar and mozzarella cheese evenly across the top. Bake uncovered for 35-40 minutes until the chicken is cooked through (check that the internal temperature reaches 165°F/74°C), and the cheese is bubbly and golden.
6. Finishing Touches:
If you like a crispier cheese topping, broil for 2-3 minutes—but watch it closely to avoid burning. Once done, remove the casserole and let it rest for about 5 minutes before serving. This helps the flavors settle and the casserole to set nicely.
Enjoy your warm, cheesy, and low-carb chicken casserole! It’s tasty, comforting, and easy to make on any night.
Can I Use Frozen Chicken for This Casserole?
Yes, you can! Just be sure to fully thaw the chicken in the fridge overnight before cooking. Pat it dry to remove excess moisture for the best texture.
Can I Make This Casserole Ahead of Time?
Absolutely! Prepare the casserole up to the baking step, cover it tightly, and refrigerate for up to 24 hours. When ready, bake as directed, adding a few extra minutes if needed.
How Should I Store Leftovers?
Store leftovers in an airtight container in the fridge for up to 3 days. Reheat gently in the oven or microwave until warmed through.
What Can I Serve with This Low Carb Chicken Casserole?
It pairs beautifully with a fresh green salad, steamed veggies like broccoli, or cauliflower rice to keep the meal low-carb and balanced.
